I was on Atkins for 2 years (about 3 years ago) and it worked great for me and I would think with Alli it would really work great the only concern I would have is the fat intake with atkins. I dont know how you do it but I know i ended up eating alot of fatty foods (lots of red meat) because I didn't have to watch that on Atkins. Thats the only glitch I could see that might cause you some discomfort. Congrates on your loss so far!