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As mentioned above, the risks of using Orlistat (or Alli with a reduced over the counter dosage) are minimal, mainly because there is no surgical procedure and no suppressing of the need for food.
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I wonder how good that is, though. If overweight people take medication to lose weight, but don't start eating less, won't they become dependent on the medication. Is it really a good thing that their appetite hasn't been suppressed?